题目：Biosensors for enzyme detection and Single molecule imaging of biomacromolecules

报告人：Dr. Rongrong Liu（A*STAR, Singapore）

主持人：关柏鸥教授

时间：2016年5月20日（星期五）上午10:00

地点：曾宪梓科学馆四楼405会议室

报告摘要：

With the rapid development of nanotechnology in the past decade, nanomaterials have been employed in wide range of applications from chemical sensors, drug delivery systems to electronics. Nanomaterials based biosensors also attract tremendous attention. The first gold nanoparticles based biosensor for sensing beta-lactamases and screening their inhibitors will be presented in this talk. The simplicity and high sensitivity of this sensing method give great potentials for clinic applications. Reversible manipulating nanostructures with specific interactions between biomacromolecues will also be discussed.

Single molecule techniques have emerged as powerful tools to study the biological processes in recent years. They overcome the limitations of ensemble measurements and one could obtain the detailed dynamic information without synchronization of the entire ensemble of molecules. In this talk, study of single conjugated polymer nanodot (CPN) will be presented. With superior optical features, CPNs have promising applications in biomedical field. Stretching and aligning DNA molecules on intelligent polymeric surface and nanostructures will also be demonstrated. This study will facilitate quantitative high-resolution optical genome mapping and high throughput analysis of interactions between protein and DNA at single molecule level.

报告人简介:

Dr. Rongrong Liu is a scientist in Institute of Materials Research and Engineering, Agency for Science, Technology and Research (A*STAR) in Singapore. She received her Bachelor and Master’s degree from Sun Yat-sen University. After graduation with PhD degree from Nanyang Technological University, she joined the world-class research institute in Singapore and continues her research. Her research interests are mainly focused on developing nanomaterials based biosensors for protein/enzyme detection and fluorescence imaging. Presently, she is working on single molecule imaging of biomacromolecues. She has published several peer reviewed papers in prestigious journals such as Angew. Chem. Int. Ed., Nanoscale, Nature photonics, Chem. Commun., Analyst. She also has 2 filed patents.

欢迎广大师生踊跃参加！

光子技术研究院

2016年5月17日